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When Teen Stress Impacts Parents’ Hearts: UGA Research Explores Surprising “Crossover Effects”

 

How does a teenager’s stress ripple through the family—beyond the emotional tension—to affect their parents’ physical health?

That’s the central question driving a newly funded research project led by University of North Carolina–Chapel Hill’s Dr. Melissa Lippold, in collaboration with Dr. Katherine Ehrlich, University of Georgia Professor of Psychology and a Distinguished Scholar at the Owens Institute for Behavioral Research, whose Health and Development Laboratory will spearhead the UGA portion of the work.

The five-year, $3.3 million study, titled “Examining the Crossover Effects of Adolescent Stress on Parent Cardiovascular Health,” is supported by the National Heart, Lung, and Blood Institute (NHLBI), with $2.4 million awarded to UGA. The project launched in September 2025 and will follow 400 parent–child pairs across Athens and surrounding areas starting this spring.

A Friendship Turned Research Partnership

Ehrlich and Lippold’s collaboration began as many great scientific partnerships do—with a shared interest and a wonderful idea.

“I had been working on a proposal about how adolescents’ stress during the transition to middle and high school might be linked to their own cardiometabolic health,” Ehrlich said. “But we kept missing the payline—sometimes by just a couple of points.”

Lippold suggested expanding the idea to include “crossover effects”—how stress in adolescents might transfer to affect parents’ health. “We quickly realized we could examine both sets of questions within the same framework,” Ehrlich recalled. “That insight turned out to be the key.”

The two researchers first met in 2005 during graduate school interviews and have been sharing ideas ever since. “We’ve been informally bouncing ideas off each other for nearly two decades,” Ehrlich said. “It’s been amazing to see how that long-term friendship evolved into a project of this scale.”

Inside the Study: Tracking Stress and Health in Real Time

Cardiovascular disease (CVD) remains one of the leading causes of death in the U.S., disproportionately affecting minority and low-income populations. Decades of evidence show that daily stressors and strong emotional reactivity to those stressors elevate risks for cardiometabolic disease and inflammation—two major predictors of CVD.

What’s new is the project’s focus on how adolescent stress might “crossover” to influence parent health. Early pilot data from Lippold’s lab revealed that, on days when adolescents experienced stressors, their parents were more likely to report negative mood, physical symptoms such as headaches or fatigue, and elevated cortisol—a stress hormone linked to heart disease.

The new study will dig deeper into those patterns. Over the next five years, the team will:

  • Recruit 400 families with children entering 6th or 9th grade.
  • Conduct in-lab assessments of stress, social relationships, and baseline health.
  • Have parents and adolescents complete two weeks of nightly surveys to capture daily stressors and emotional responses.
  • Follow each family for 18 months to see how adolescent stress predicts changes in parent cardiovascular health and inflammatory markers.

By combining new primary data with analyses of an existing parent-child dataset, the research will test whether findings hold across different racial, ethnic, and socioeconomic groups—providing a rare opportunity to examine health disparities in stress transmission.

Why It Matters

Parenting adolescents can be both rewarding and stressful. This project aims to uncover how those daily stressors matter for parents’ physical health and identify modifiable pathways—such as poor sleep, worry, or strained family communication—that might amplify or buffer those effects.

Ultimately, the findings will guide the design of future interventions to help parents respond to teen stress in ways that protect their own cardiovascular health. “If we can pinpoint the mechanisms linking adolescent stress to parent health, we can design strategies that promote resilience in both generations,” Ehrlich explained.

The Human Side of Science

For Ehrlich, the project reflects the unpredictable but rewarding path of research. “Research trajectories often look linear in hindsight,” she said, “but in reality, they’re shaped by timing, collaboration, and a fair amount of luck. This grant is a perfect example—it started as a companion idea and became the centerpiece of our next five years.”

She also praised the Owens Institute for Behavioral Research and UGA’s Center for Family Research for their support. “The OIBR team was incredible, especially during those chaotic submission cycles when I had two or three proposals going at once,” she said.

And while the work is challenging—tracking participants over years, managing complex data systems—Ehrlich finds joy in the teamwork behind it all. “When everything is running smoothly—data coming in, students learning, analyses progressing—it feels like we’re all part of something bigger. That’s what I love most about this work.”

Learn More

Families interested in participating or following the project’s progress can visit the Health and Development Laboratory website: https://www.healthanddevelopmentlaboratory.com

Written by: Andrea Horsman
November 13, 2025

Harnessing AI to Advance Maternal Health

Soroya McFarlane (left) and Ishtiaque Fazlul (right)
Soroya McFarlane (left) and Ishtiaque Fazlul (right)

When Dr. Soroya McFarlane, OIBR Grant Development Program Graduate and assistant professor in Communication Studies, first began exploring how artificial intelligence (AI) could intersect with her maternal health research, she wasn’t aiming to create just another digital tool. Instead, she imagined a way to transform how critical, often lifesaving, information is shared with women and their families. That vision is now coming to life through THRIVE AI, a groundbreaking project supported by the NIH AIM-AHEAD Program for Artificial Intelligence Readiness (PAIR).

From the THRIVE Project to THRIVE AI

McFarlane’s earlier initiative, the THRIVE Project, focused on empowering families during childbirth with accessible, evidence-based resources. As she looked for ways to expand its reach, she identified natural language processing (NLP) as a promising tool to simplify complex scientific information into everyday language.

Her path forward became clear when she discovered the AIM-AHEAD PAIR program, which offered both advanced AI training and funding. “It was the perfect opportunity,” McFarlane explains. “PAIR gave me the tools to deepen my expertise in AI while also supporting my mission to provide resources for birth companions and families.”

Collaboration Sparked at OIBR

The seeds of this project were planted during an OIBR working group meeting on social science and computational methods. There, McFarlane connected with Dr. Ishtiaque Fazlul, Co-PI, and OIBR affiliate and assistant professor in the College of Public Health and School of Public & International Affairs. Their shared interests—maternal health communication and computational approaches—made collaboration a natural fit. Together, they bring complementary expertise: McFarland in communication science, Fazlul in causal inference and machine learning.

OIBR has been a key connector throughout this journey, helping McFarlane navigate UGA’s research ecosystem and build the infrastructure needed to secure funding and launch the project.

Addressing Black Maternal Health Disparities

In the U.S., Black women are three to five times more likely to die from childbirth-related causes than their white counterparts—regardless of education, geography, or pre-existing conditions.

For McFarlane, many of these inequities are rooted in fundamental communication problems: women not being heard, medical information shared in inaccessible ways, and misaligned or inappropriate treatments.

“Communication science gives us theories and strategies to contribute to solutions,” she says. “By applying AI thoughtfully, we can create interventions that ensure Black women and their families feel informed, supported, and heard.” 

Community at the Center

One of the most rewarding aspects of the THRIVE project, McFarlane emphasizes, is its community-engaged approach. From the earliest proposal stages, community partners have been active collaborators, helping shape the project’s direction and ensuring that the tools being built reflect real-world needs.

“The most gratifying part,” she shares, “is having communities as experts by experience, not just as research subjects. That validation keeps us focused on creating solutions with real-world impact.”

Navigating Surprises and Challenges

Even with UGA’s nearly 50-year history of artificial intelligence research, McFarlane’s team discovered they were the first on campus to attempt direct procurement with OpenAI. “It was surprising to realize how new some aspects of this work still are within our institution,” she notes.

Another ongoing challenge is the fast pace of the AI field. While academic research is methodical by design, AI evolves daily. “We’re learning as we go—building expertise and conducting studies—while also making sure our results aren’t outdated by the time they’re complete,” McFarlane says.

Building a National Network

Through the PAIR program, McFarlane has gained access to a national network of scholars working at the intersection of AI and health equity. Partnerships with institutions like Meharry Medical College are opening doors for collaboration with computer science faculty and students tackling similar projects. These connections not only expand the scope of THRIVE AI but also enhance its potential to positively impact maternal health outcomes on a national scale.

Looking Ahead

Over the next five years, McFarlane envisions the THRIVE platform becoming a widely adopted resource across hospitals nationwide. The goal is not only to improve clinical outcomes but also to transform the birthing experience, reducing fear, increasing satisfaction, and helping underserved communities take an active role in their care.

“The real measure of success,” McFarlane reflects, “is when research moves off the page and into tools that directly support families.”

Learn More

The Thrive Project

The Conchus Lab

 

Written by: Andrea Horsman. Oct. 10, 2025

Research with Impact: Dr. Mohammad Rifat Haider Tackles Harm Reduction for High-Risk Communities in the Deep South

When it comes to cutting-edge research that addresses urgent public health issues, Dr. Mohammad Rifat Haider is leading the way. An assistant professor in Health Policy and Management at the UGA College of Public Health, Dr. Haider is using technology and compassion to better understand and support marginalized populations—particularly men who engage in chemsex, a practice involving planned substance use to enhance sexual experiences.

Recently awarded an NIH R21 grant through the National Institute on Drug Abuse (NIDA), Dr. Haider’s work centers around Ecological Momentary Assessment (EMA) to track high-risk behaviors and develop real-time harm reduction strategies. The study seeks to illuminate not only how chemsex is practiced—particularly in the Deep South—but also what harm reduction methods are used or neglected by participants.

“This is an underexplored area in U.S. research,” Haider explains. “Much of what we know about chemsex comes from European studies. We’re looking to fill that gap—especially in Southern states, where cultural norms and healthcare access differ significantly.”

The OIBR Grant Development Program: A Launchpad for Success

Dr. Haider credits the OIBR Grant Development Program (GDP) with playing a pivotal role in his success as a researcher. “The GDP completely reshaped how I think about grants,” he says. “It pushed me to elevate my ideas, challenged my assumptions, and ultimately helped me craft a competitive proposal.”

His R21 grant proposal emerged directly from his time in the GDP. The program’s grant pitch session, faculty mentorship, and peer feedback gave him critical insight into how reviewers think. One such moment came when he was advised to rethink a prevalence-focused study design in favor of a more intervention-oriented, harm-reduction model—an insight that proved transformative.

“That was an eye-opener,” Haider recalls. “It showed me that I wasn’t thinking big enough—or strategically enough—for NIH funding.”

Beyond the technical support, Haider emphasizes the mentorship and community the GDP offers.

“I can’t thank the OIBR team enough—Jody, Dawn, Chris, Kim, and Stacie… they were all incredibly helpful throughout the process,” he adds. “It wasn’t just professional guidance; it was a team effort, and it never felt transactional. They genuinely wanted me to succeed.”

Haider’s experience underscores the broader impact of OIBR’s mission: to empower early-career researchers with the tools, support, and confidence needed to win external funding and tackle complex social and behavioral challenges.

A Tech-Driven, Human-Centered Approach

Unlike traditional behavioral studies, Dr. Haider’s research leverages EMA technology, prompting participants to respond to brief mobile surveys twice daily. These real-time updates gather data on chemsex behavior, venues, and any harm reduction techniques employed—such as carrying naloxone, pre-programming emergency contacts, or using condoms or PrEP.

This real-time data collection is the foundation for a future Just-In-Time Adaptive Intervention (JITAI), a mobile app designed to deliver timely support. For instance, if a participant enters a known high-risk setting, GPS data could trigger reminders about harm reduction tools.

“We’re not telling people to stop,” says Haider. “We’re meeting them where they are, providing knowledge and tools so they can make safer choices.”

Strategic Partnerships

This work wouldn’t be possible without the collaborative effort behind it. Dr. Haider co-leads the project with colleague and mentor Dr. Nate Hansen and is supported by collaborators like Dr. Jeremy Gibbs from UGA’s School of Social Work. Their collective experience spans multiple NIH-funded studies and outreach to hard-to-reach communities.

STARR Lab: Building a Research Hub for Risk Reduction

Dr. Haider’s growing research collective—aptly named the STARR Lab (Social Technology and Risk Reduction)—includes faculty, (Drs. Nate Hansen, Tamora Callands, Liyuan Wang, Jeremy Gibbs), doctoral students, and undergraduates working across several NIH-funded projects. The group’s long-term goal is to create a centralized digital platform housing intervention tools, research outputs, and engagement features for participants and partners.

“Technology is integral to everything we do,” Haider explains. “From data collection to intervention delivery, we’re building systems that are responsive, scalable, and rooted in evidence.”

From Resilience to Results

If there’s a theme that runs through Haider’s work, it’s resilience. Whether studying people who inject drugs, individuals experiencing homelessness, or LGBTQ+ youth navigating identity and risk, Haider sees his participants not as problems to be solved, but as experts in survival.

“These folks are already resilient. My job is to channel that resilience toward healthier outcomes,” he says. “We’re not starting from zero—we’re building on what they already know and do.”

A Scholar on the Rise

Dr. Haider’s growing list of accolades includes an OIBR Distinguished Scholar designation and the 2024 OIBR Rising Star Award. His work has been featured at major conferences, including the American Public Health Association, and is rapidly gaining national attention.

“Three years ago, if someone told me I’d have three NIH grants, I would’ve thought it was a cruel joke,” Haider says with a laugh. “But here we are—and it’s because I had the right support system.”

Written by: Andrea Horsman
Sept. 15, 2025